Your Thyroid Problem and Your Breast Cancer Risk

A 36 year-old spunky, bold, compassionate mother of two (and good friend of mine) discovered her own breast cancer. It wasn’t even a lump, more of a “leatheriness,” she said, and she almost hated to go get it checked out, as it felt like something she might just be imagining. But alas, it was not an overactive imagination. It was advanced breast cancer requiring chemotherapy, radiation, and mastectomy.

When I was in med school, I was taught that breast cancer under the age of 40 was RARE. Yet, every month or so it seems as if I hear a story of someone younger than 40 getting breast cancer. Good friends and acquaintances. Indeed, the statistics are changing, and it is a documented, terrifying fact that breast cancer rates are increasing in women younger than 40 years old, particularly the rates of advanced breast cancer requiring chemotherapy and radiation. (1)

(This post will not be about  breast cancer. It’s just going to briefly touch on the idea that thyroid condition patients are at higher risk for breast cancer, a fact I don’t think they all know.)

“Could my thyroid cancer have anything to do with my breast cancer?”

My friend asked her breast surgeon: “Could the thyroid cancer I had when I was younger have anything to do with my breast cancer?”

His reply to her question was apparently a flat-out NO.

He told her wrong.

If you read no further than this next paragraph, here’s my take-home:

If you have thyroid disease, I encourage you to be assertive about breast monitoring. Those with thyroid disease deserve to know that certain thyroid conditions are definitely associated with an increased risk of breast cancer.  Print off any of the articles I list in my references which may apply to you and take them into your healthcare provider to develop a breast monitoring plan together.

Thyroid Cancer Points to a Woman at Higher Risk for Breast Cancer

Thyroid cancer is associated with an increased breast cancer risk. In 2015, Dr. Jennifer Kuo (M.D.) of Columbia University presented pooled data from something called the Surveillance, Epidemiology, and End Results Database-9 (between the years of 1973-2011), reporting that patients who had had thyroid cancer were at an increased risk for developing breast cancer in comparison to the general population.

The 10-year risk for developing breast cancer at 40 years old was 5.6% after having thyroid cancer, while for the general population, breast cancer risk was only 1.5%. By age 50, the rate increased to 12.8% while the general population hung out at about 2.4%.

Simple recap for those with a history of thyroid cancer:

  • At age 40, 5.6% risk of breast cancer versus 1.5% risk in “normal people.”
  • At age 50, 12.8% risk of breast cancer versus 2.4% in “normal people.” (2)

Review of different data by other researchers indicated that a woman who had survived thyroid cancer was 1.18 times more likely to develop breast cancer than controls. Interestingly, this review also indicated the risk went the other way too! A breast cancer patient was 1.55 times more likely to develop thyroid cancer than the general population. (3)

So the answer is not NO. The answer is YES.

If you’ve had thyroid cancer, you and your doctor need to know that you’re at a higher risk for breast cancer and should take steps for monitoring your breast tissue.

Will Continue Next Post

In the next post, I’ll briefly cover other thyroid conditions and what the research indicates regarding breast cancer risk. And of course link it to food and encourage you to stick with whole, real food rich in vegetables and fruits! Both you AND your kids.

Have a wonderful Monday! Remember something that really makes you smile today. Think on it all day. And let that smile out. Share it. The world changes only as people’s hearts change. Your smile and joy can change people’s hearts.

Terri

 

Citations:

(Doing the citations is the biggest headache of my scientifically related posts, but I think citations are monumental to include–and especially helpful when the citation is linked to the piece of information in the article so you don’t have to go searching for which article information came from. When I re-write paragraphs, it messes the citation order ALL up. What a headache. So please, let me know if something doesn’t look right and I need to look at it again. Or if you’re a scientific writer who knows the trick to doing citations more easily, please do share!)

1. Johnson RH,  Chien FL, Bleyer A. Incidence of Breast Cancer With Distant Involvement Among Women in the United States, 1976 to 2009. JAMA. 2013;309(8):800-805; doi:10.1001/jama.2013.776. http://jama.jamanetwork.com/article.aspx?articleid=165625

2. Thyroid-Cancer Survivors at Higher Risk of Breast Cancer. Medscape Web Site. http://www.medscape.com/viewarticle/845605. Published June 1, 2015.

3. Nielson SM et al. The Breast-Thyroid Connection Link: A Systemic Review and Meta-Analysis. Cancer Epidemiol Biomarkers Prev. February 2016 25; 231. doi: 10.1158/1055-9965.EPI-15-0833. http://cebp.aacrjournals.org/content/25/2/231.abstract

9 thoughts on “Your Thyroid Problem and Your Breast Cancer Risk

  1. Bob Niland

    re: …thyroid condition patients are at higher risk for breast cancer…

    They’re at higher risk for lots of things (like CVD), and everyone needs to assume that they are hypothyroid, until proven otherwise (and probably not by their current physician).

    I may be jumping the gun on your follow-up article, but our malfunctioning milieu is:

    ☤ Iodine deficiency is rampant, and actually got worse when low-salt mania arose a few decades ago (not that iodized salt was an ideal way to get it, but even that support is now deminimus).

    ☤ Iodine RDA is almost certainly too low, at 150mcg/day for the US. 500-1000 might be a healthier target, and possibly more.

    ☤ Iodine is being out-competed at the thyroid by pervasive non-native halogen compounds in water, processed foods and our personal environments. Municipal water treatment residues are in my view a significant concern. Chloramine is a particular problem, as it’s a very persistent agent (you can’t even make fermented food with it, and letting your water stand overnight won’t clear it). Fluoridation needs a hard reconsideration (it’s unnecessary for dental health when low carb).

    ☤ Processed foods contain numerous other agents that are likely endocrine disruptors.

    Even if you suspect thyroid, finding out is a challenge.

    ☤ The Standard of Care is to test TSH only (which is a pituitary test, and not even a thyroid test per se).

    ☤ You then get a declaration of “normal” when it is in fact either too high (suggestive of hypo) or too low (suggestive of hyper).

    ☤ Even when sky high, the treatment offered is apt to be T4 only (and not the T3 or T3+T4 really needed).

    So be sure to ask for tests: fT3, fT4, rT3 and TA. The response may be telling.

    If this mess has contributed to cancer, well that’s its own can of worms:
    https://www.cureality.com/forum/topics.aspx?ID=18684

    Reply
    1. thehomeschoolingdoctor Post author

      Not jumping the gun on my next article at all. I don’t plan (yet, due to time constraints) on elaborating on why I think the thyroid or the breasts are out of control. All I want women to know, especially the under 40 crowd!!!!! (as they’re the ones who aren’t getting breast screening yet are having the frightening increase in advanced disease), is that if they have thyroid issues, they’d better implement a breast plan. Mammogram screenings are being reduced per guidelines, which I understand there’s also the risk of over diagnosing lesions that will regress so isn’t necessarily the wrong thing, but thyroid women just need to be vigilant. Know your risk factors.

      I will talk ever briefly about the lack of complete clinical workup for thyroid patients. And I agree that women are iodine deficient and probably plays a role. I have an iodine series and am EVER so slowly working through that (with phenomenal 4 kids in tow) with regard to the different body tissues. Haven’t written up breast yet.

      Bottom-line: I don’t want women like my friend with knows thyroid issues to NOT be aware they’re in a higher risk category.

      Bob, I hope you’re doing really well! We’re great here! Too busy but it’ll stabilize! Good to see your comment in the box.

      Reply
  2. Tim Steele

    Good post, but to answer your citation question, here’s a trick I learned in school that even the most APA-compliant professors love, and my fellow students hail me a hero, for devising.

    Visit “Google Scholar” ( https://scholar.google.com/ )

    Copy and paste the full title of your paper into the search bar, for instance, your first citation, “Incidence of Breast Cancer With Distant Involvement Among Women in the United States, 1976 to 2009.”

    Click the find icon, and your paper should appear.

    Now, see the little word “cite” underneath the description? Click it and you will get perfectly formatted citations in every format, APA, Chicago, MLA, etc.

    Copy and paste the cite that fits your format. I like APA. In this case:

    Johnson, R. H., Chien, F. L., & Bleyer, A. (2013). Incidence of breast cancer with distant involvement among women in the United States, 1976 to 2009. Jama, 309(8), 800-805.

    To make it more “blog friendly” you can insert a hyperlink somewhere in the cite, but anyone should be able to find it simply by Google Scholar-ing the title.

    Reply
    1. thehomeschoolingdoctor Post author

      That is wonderful. I should have asked four years ago. I’m doing cartwheels, I’m so relieved! I’d write my articles, then I’d spend a couple of days with the citations. I asked someone a couple of years ago, but they didn’t show me this. This rocks. THANK YOU!!!!!

      Reply
  3. Tim Steele

    Oh, also, if you adopt an APA format, simply use author’s last name and date for the in-line citations, ie. (Johnson, et al. 2013). Then alphabetize your cites for easy reference.

    I hate the current system used in most journals with a hyperlinked number, as you say, they get messed up when re-writing, but also, I like to see the year as I’m reading the text. I get excited more seeing lots of 2015, 2016 cites than a mess of 1990’s and earlier.

    We should develop a “blog standard” for referencing scientific papers, eh?

    Reply
    1. thehomeschoolingdoctor Post author

      Good idea too. I don’t remember all the formats, so I was doing Terri Format, knowing that anything someone needed to get to the journal and article was included. I might try the APA format out in the near future and see how I like that. I like the numbers because they’re less intrusive, especially for lay readers who get lost. But I just know I’m going to mess up the numbers in my articles. Oh, well, people should be able to tell they can ask me a question anytime to point them in the right direction. 🙂

      Heck, there should be standards that blogs even reference papers! That makes me bristle! Where did they read that?

      Happy Monday.

      Reply
  4. andthreetogo

    Fascinating! I never knew this, but considering that the ladies doctor didn’t know either makes me feel better 🙂 Miss chatting with you. I added the wordpress app back onto my phone to stay more connected, so fingers crossed haha. I hope all is well in your life with you and your lovely family! xoxo

    Reply
    1. thehomeschoolingdoctor Post author

      Dear Jenny, All is well here. I miss chatting with you too! Life changes and evolves, doesn’t it?! Kind of fun, kind of bittersweet. Ha! Good luck with the WordPress app. I never had much luck with that one. But you always know where I am if something comes up!

      Reply
  5. Pingback: Your Thyroid Problem and Your Breast Cancer Risk, Part II | The HSD

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